A rare case of cervical Rhabdomyosarcoma in an Adolescent- A case report

Leek Mei Lim, Suguna Subramaniam, Tamilarasi Renganathan, Ana Vetriana Abd Wahab

Abstract


We present a rare case of cervical embryonic rhabdomyosarcoma (ERMS) in adolescents, managed with fertility-sparing surgery and chemotherapy. This type of malignant tumour is rare, and the management is not codified. A 15-year-old girl presented with a tongue-like mass per vagina and abnormal discharge. She underwent vaginoscopy under anaesthesia, which revealed a polyp from the endocervix. Hysteroscopic resection was performed, and histopathology showed ERMS. Postoperative imaging suggests the presence of residual local disease without evidence of distant metastasis. A multidisciplinary team (MDT) meeting was conducted, and the family opted for fertility-sparing management. The patient underwent repeat hysteroscopy-guided local excision, followed by eight cycles of chemotherapy, with close surveillance. In conclusion, polyps are rather odd in adolescents; malignancy should always be suspected. Fertility-sparing surgery with chemotherapy is a plausible option in well-selected cases.


Keywords


Cervical Embryonal Rhabdomyosarcoma; ERMS; adolescent polyp; Paediatrics and adolescent gynecology; PAG; Fertility sparing surgery; case report

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References


Jayi S, Bouguern H, Fdili FZ, et al. Embryonal rhabdomyosarcoma of the cervix presenting as a cervical polyp in a 16-year-old adolescent: A case report. J Med Case Rep 2014; 8(1): 241.

Bell SG, Konney TO, Appiah-Kubi, et al. Two rare presentations of embryonal rhabdomyosarcoma of the cervix in teenagers at a low-resource teaching hospital in Ghana: A case series. Gynecol Oncol Rep 2021; 36: 100750.

Buruiana FE, Gupta B, Singh K. Rhabdomyosarcoma of the cervix in teenagers - Is fertility preservation a feasible option? Gynecol Oncol Rep 2020; 34: 100677.

Kriseman ML, Wang WL, Sullinger J, et al. Rhabdomyosarcoma of the cervix in adult women and younger patients. Gynecol Oncol 2012; 126(3): 351-6.

Jo VY, Fletcher CD. WHO classification of soft tissue tumours: An update based on the 2013 (4th) edition. Pathology 2014; 46(2): 95-104.

Villella JA, Bogner PN, Jani-Sait SN, Block AM, Lele S. Rhabdomyosarcoma of the cervix in sisters with review of the literature. Gynecol Oncol 2005; 99(3): 742-8.

Dondi G, Porcu E, De Palma A, et al. Uterine preservation treatments in sarcomas: Oncological problems and reproductive results: A systematic review. Cancers (Basel). 2021; 13(22): 5808.




DOI: http://dx.doi.org/10.17576/JSA.2024.1402.04

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